The goal of Information and Communication Technology (ICT) was to make our lives easier (i.e., by providing faster communications around the globe, efficacy in work processes, and so on). If modern technology was designed to empower us, to set us free, and to leave us satisfied, why do we often feel (techno-) stressed due to the use of this technology? This paper unravels a modern disease caused by inability to cope with computer technology in a healthy manner called Technostress. Technostress scale, a twenty – two item Likert-type, two sub-scale questionnaires designed for the study was administered on two hundred and one samples drawn from five faculties in National Open University of Nigeria (NOUN) and five Commercial banks in Port Harcourt metropolis, Nigeria. The data were analyzed using t-test, Correlation and ANOVA statistics. The results revealed that academic staff manifested higher levels of technostress than the employees from the banking sector, a positive correlation was observed between computer hassles and stress reaction. In conclusion, ICT training and stress management were highlighted as solutions for technostress in the two human industries.