Amyotrophic lateral sclerosis (ALS) patients cannot control their muscle except eyes in the later stage of the disease progress. This paper aims to develop an eye-based assistive system that is controlled by the eye gaze to help ALS patients improve their life quality. Two main functions are proposed in this paper. The first one is called HelpCall that can detect the users’ eye gaze to active the corresponding events. ALS patients can “talk” with other people more easily by looking at specific buttons in the HelpCall system. The second one is an eye-control browser that allows the users browsing web pages in Internet. We design an interface that embeds the IE browser into several buttons controlled by the user eye gaze. ALS patients can visit the Internet only using their eyes in our proposed system. This paper discusses our ideas for the assistive system and then describes the design and implementation of our proposed system in details.