In order to be competitive enterprises are rapidly changing in terms of technology and moving towards emerging technology trends. Recently cloud computing has emerged as a revolutionary trend and become an integral part of business organizations. However, it is important for organizations to consider a best cloud computing infrastructure that may best fit to the business needs. In this study different types of cloud computing infrastructures have been discussed. The study discusses and analyzes the essential requirements for effective cloud computing infrastructure and concludes the best infrastructure requirements for business organizations before they build a cloud computing infrastructure.