Inter-Schools Collaboration and Information Management System are technologies that support Knowledge Management (KM) in organizations, specifically - knowledge generation, codification, and transfer. The use of KM in organizations is now widely recognized and expected to be an important part of organizational practices. The study focused on establishing an Inter-Schools Collaboration and Information Management System that captures various aspects of school operations for Kisii County secondary schools. A KM system was designed, tested and implemented. The key areas of the Inter-Schools Collaboration and Information Management System that arose from the analysis done include; academics, student admissions, accounts, examinations and sports that encompass the bulk of the information critical for Inter-Schools Collaboration and Information Management System for school management. The researcher employed UML (unified Modeling language) in presenting the Inter-Schools Collaboration and Information Management System at the design stage. The results of the design phase were translated into program Codes using PHP, javascript, HTML, MySql and the wamp server as the implementation environment. The study provided platform that has made it easier, faster, and cheaper to access schools data from the same access point for many secondary schools in Kisii County.