This paper's major goals are to present an overview of the current research trends in information systems (IS), investigate the causes of those trends, evaluate the relevance and effectiveness of those trends, and then suggest strategies to enhance IS research. The study builds a foundation for understanding information systems research. The concepts of positivism, interpretivism, qualitative, and quantitative research are discussed in this paper along with current trends in information system research methodologies. It also highlights the distinctions between qualitative and quantitative approaches and provides justification for the use of case studies in information systems. The study's methodology involved online desk research, with a primary focus on studies between 2018 and 2022.